Detoxification is the cleansing procedure (Panchakarma) to purify the whole body by eliminating accumulated toxins. Panchakarma (five cleansing procedures) includes Vamana (medicated emesis), Virechana (medicated purgation), Vasti (medicated enema), nasya (nasal instillation) and Raktamokshana (blood letting). When a healthy person undergoes Panchakarma procedures, it has a preventive, restorative and rejuvenative effect by enhancing the body’s immunity. Rejuvenation must be done after detoxification of the body, so it helps in making the body more receptive to assimilate Rasayana medicines. Rasayana procedures tone up the muscles, strengthen the system, invigorate the body and calm the mind. It promotes longevity and restores vitality. Herbs, herbal oils and powders used in this process impart a glowing lustre to the skin.